Article ID Journal Published Year Pages File Type
10833544 Molecular Genetics and Metabolism 2012 6 Pages PDF
Abstract
► T‐cell receptor excision circle (TREC) count by PCR shows thymic output of T cells. ► An EBV B‐cell line was made with a single copy of the TREC sequence. ► Graded TREC-EBV cell numbers added to T-depleted blood constituted calibrators. ► TREC copy number was proportional to the number of TREC-EBV cells. ► TREC-EBV cells are as a universal cellular calibrator for TREC assays.
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