| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10833564 | Molecular Genetics and Metabolism | 2014 | 6 Pages |
Abstract
Pyruvate was effective even in bedridden patients with OXPHOS disorders, at least in the short term. Clinical trials with more patients and less severe disabilities are necessary to evaluate the long-term efficacy of this treatment. Biomarkers other than lactate and pyruvate need to be identified to biochemically monitor the efficacy of this treatment.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Tatsuya Fujii, Fumihito Nozaki, Keiko Saito, Anri Hayashi, Yutaka Nishigaki, Kei Murayama, Masashi Tanaka, Yasutoshi Koga, Ikuko Hiejima, Tomohiro Kumada,