Article ID Journal Published Year Pages File Type
10833755 Molecular Genetics and Metabolism 2012 10 Pages PDF
Abstract
► Various aminoglycosides that suppress nonsense mutations with were tested. ► NB54 and NB84 suppressed a nonsense mutation in an MPS I-H mouse. ► NB84 significantly reduced GAG levels in the Idua-W392X mouse.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
The designer aminoglycoside NB84 significantly reduces glycosaminoglycan accumulation associated with MPS I-H in the Idua-W392X mouse
Authors
, , , , , , , ,