| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10833762 | Molecular Genetics and Metabolism | 2012 | 6 Pages |
Abstract
⺠The cell-surface LDLR is cleaved between ligand-binding repeats 4 and 5. ⺠The cleavage enzyme is secreted from the cells. ⺠The truncated LDLR is unable to bind LDL. ⺠The half-life of the truncated LDLR is similar to that of the full-length LDLR. ⺠The truncated LDLR constitute approximately 1/3 of the cell-surface LDLR.
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Authors
Kristian Tveten, Thea Bismo Strøm, Jamie Cameron, Ãystein L. Holla, Knut Erik Berge, Trond P. Leren,