Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10833786 | Molecular Genetics and Metabolism | 2012 | 7 Pages |
Abstract
⺠Patients with type 2 diabetes followed prospectively for 6 years. ⺠Impact of superoxide dismutase-1 (SOD1) gene variants on vascular complications. ⺠Allelic association with the prevalence of microalbuminuria at baseline. ⺠Allelic associations with increased risk of death from cardiovascular causes. ⺠Results consistent with SOD1 protection against oxidative stress.
Keywords
UTREGFRACEROSangiotensin converting enzymeUAEGenetic epidemiologyanalysis of varianceANOVAOxidative stressSODSuperoxide dismutaseCardiovascular complicationsSudden deathuntranslated regionestimated glomerular filtration ratehazard ratioodds ratioDiabetic nephropathySingle nucleotide polymorphismSNPReactive oxygen species
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Authors
Ana LuÃsa Neves, Kamel Mohammedi, Nathalie Emery, Ronan Roussel, Frédéric Fumeron, Michel Marre, Gilberto Velho,