| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10833863 | Molecular Genetics and Metabolism | 2011 | 7 Pages |
Abstract
⺠Tag SNPs of the Acetyl-CoA carboxylase beta gene (ACACB) were studied in women. ⺠One SNP was significantly associated with morbid obesity. ⺠Two SNPs were associated with type 2 diabetes, independently of BMI. ⺠EMSA suggested the binding of glucocorticoid receptor and serum response factor. ⺠ACACB polymorphisms appear to influence the risk of obesity and type 2 diabetes.
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Authors
J.A. Riancho, L. Vázquez, M.A. GarcÃa-Pérez, J. Sainz, J.M. Olmos, J.L. Hernández, J. Pérez-López, J.A. Amado, M.T. Zarrabeitia, A. Cano, J.C. RodrÃguez-Rey,