Recombination mapping using Boolean logic and high-density SNP genotyping for exome sequence filtering

Article ID	Journal	Published Year	Pages	File Type
10833883	Molecular Genetics and Metabolism	2012	8 Pages	PDF

Abstract

âº A method of using SNP chips and Boolean logic for recombination mapping. âº The likelihood of a double crossover between informative SNPs is negligible. âº Recombination maps correlate with linkage maps. âº Recombination maps filter exome sequence variants.

Keywords

single nucleotide variants Exome sequencing Recombination Mapping Linkage

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

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Recombination mapping using Boolean logic and high-density SNP genotyping for exome sequence filtering

Authors

Thomas C. Markello, Ted Han, Hannah Carlson-Donohoe, Chidi Ahaghotu, Ursula Harper, MaryPat Jones, Settara Chandrasekharappa, Yair Anikster, David R. Adams, NISC Comparative Sequencing Program NISC Comparative Sequencing Program, William A. Gahl,