| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10833911 | Molecular Genetics and Metabolism | 2012 | 5 Pages |
Abstract
⺠For the first time, Dyrk1a has been shown to have antioxidant properties by activating NQO1 gene expression in liver of mice. ⺠Our results demonstrate a link between DYRK1A and NRF2 signaling pathway. ⺠DYRK1A activates NRF2 by a direct or by an indirect mechanism implicating ERK1/2.
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Authors
Christophe Noll, Asma Tlili, Clémentine Ripoll, Ludovic Mallet, Jean-Louis Paul, Jean-Maurice Delabar, Nathalie Janel,