| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10833915 | Molecular Genetics and Metabolism | 2012 | 8 Pages |
Abstract
⺠Severely obese individuals show low-grade inflammatory state. ⺠Variability of the inflammatory profile assessed by CRP levels was observed. ⺠SNPs in IFI30, CD163, CXCL9 and TSLP were tested for association with CRP levels. ⺠Significant association between IFI30 rs11554159 and CRP levels was identified. ⺠IFI30 SNPs could contribute to the variability of CRP levels in obesity.
Keywords
IDFchemokine (C-X-C motif) ligand 9CXCL9CD163HDL-Chs-CRPLDL-CHWEDBPMAFcDNAHigh-sensitivity CRPcomplimentary DNAcardiovascular diseaseHardy-Weinberg equilibriumInternational Diabetes FederationCVDMetabolic syndromebody mass indexBMILinkage disequilibriumminor allele frequencydiastolic blood pressureBlood pressurehigh-density lipoprotein cholesterolMETSC-reactive proteinCRPLow-density lipoprotein cholesterol
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Authors
Geneviève Faucher, Frédéric Guénard, Luigi Bouchard, Véronique Garneau, Valérie Turcot, Alain Houde, André Tchernof, Jean Bergeron, Yves Deshaies, Frédéric-Simon Hould, Stéfane Lebel, Picard Marceau, Marie-Claude Vohl,