Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10833918 | Molecular Genetics and Metabolism | 2012 | 6 Pages |
Abstract
⺠Here we assessed the distribution of CD38 NADase activity in a healthy population. ⺠The mean value of CD38 NADase activity was 0.051 ± 0.023 mU/mg (0.010-0.099 mU/mg). ⺠TNF-α rs1800629 resulted the main predictor, followed by Age and CD38 184 C > G rs6449182. ⺠The use of rs1800629 and rs6449182 as predictive markers of CD38 activity, point toward a pharmacogenomic use.
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Authors
Valeria Polzonetti, Francesco M. Carpi, Daniela Micozzi, Stefania Pucciarelli, Silvia Vincenzetti, Valerio Napolioni,