| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10835123 | Nitric Oxide | 2012 | 7 Pages |
Abstract
⺠Doxycycline is known to inhibit matrix metalloproteinase (MMP). ⺠This effect is associated with improved vascular function in hypertension. ⺠We showed that doxycycline exerts antioxidant effects and improves NO availability. ⺠These effects may contribute to its antihypertensive effects.
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Authors
Michele M. Castro, Elen Rizzi, Carla S. Ceron, Danielle A. Guimaraes, Gerson J. Rodrigues, Lusiane M. Bendhack, Raquel F. Gerlach, Jose Eduardo Tanus-Santos,