Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10835124 | Nitric Oxide | 2012 | 5 Pages |
Abstract
⺠We evaluate the ability of bacteria to develop a resistance to exogenous NO. ⺠Nitrosothiol nanoparticles were utilized as an exogenous antimicrobial model. ⺠Prolonged exposure to sub-therapeutic NO did not result in increased resistance. ⺠Single-dose exposure to bactericidal NO did not result in increased resistance. ⺠These assays may serve as a blueprint for future NO resistance studies.
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Authors
Benjamin J. Privett, Angela D. Broadnax, Susanne J. Bauman, Daniel A. Riccio, Mark H. Schoenfisch,