| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10835125 | Nitric Oxide | 2012 | 8 Pages |
Abstract
⺠Mitochondrial NADH oxidation released NO from a nitrosyl ruthenium complex. ⺠NO2 formation and OAT mechanism were apparently involved. ⺠NO released caused protein-thiols oxidation and induced the mitochondrial permeability transition. ⺠Cytochrome c was released from mitochondria. ⺠This denotes a potential specific action against tumor cells.
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Authors
Fernando P. Rodrigues, Cezar R. Pestana, Ana C.M. Polizello, Gilberto L. Pardo-Andreu, Sérgio A. Uyemura, Antonio C. Santos, Luciane C. Alberici, Roberto S. da Silva, Carlos Curti,