| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10835126 | Nitric Oxide | 2012 | 10 Pages |
Abstract
⺠NO controls the cell cycle at both the G1/S transition and the S and G2/M phases. ⺠NO controls p21Cip1/Waf1 expression in a biphasic manner. ⺠The expression of p21Cip1/Waf1 is controlled by the BRCA1/Chk1/p53 pathway. ⺠The activation of p38MAPK down-regulates the NO-mediated p21Cip1/Waf1 expression.
Keywords
EGFRp38MAPKMKP-1AEBSFE-64TRISCDKIECLPMSFPRBqRT-PCRATRPVDFNP-40Tween-20MAP kinase phosphatase 1DETACDKFACSDMEMJnk4-(2-aminoethyl)-benzenesulfonyl fluorideSPER/NOFBSSB2021904,5-diaminofluorescein diacetateataxia telangiectasia mutatedc-Jun N-terminal kinaseDEA/NODETA/NODMSOMAPKSDS–PAGEEDTAEthylenediaminetetraacetic acidfluorescence-activated cell scanningpolyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfateenhanced chemiluminescenceTris(hydroxymethyl)aminomethaneCell proliferationApoptosisATMDiethylenetriamineDimethyl sulfoxidefetal bovine serumNeuroblastoma cellsphenylmethylsulphonyl fluorideDulbecco’s modified eagle’s mediumcyclin-dependent kinase inhibitorNitric oxideQuantitative reverse transcriptase-polymerase chain reactionretinoblastoma proteinmitogen-activated protein kinasePoly(vinylidene difluoride)Cell cycleBRCA1cyclin-dependent kinaseEpidermal growth factor receptor
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Authors
Marlies Van de Wouwer, Célia Couzinié, Miguel Serrano-Palero, Ãscar González-Fernández, Clara Galmés-Varela, Paula Menéndez-AntolÃ, Laura Grau, Antonio Villalobo,