| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10835591 | Peptides | 2012 | 8 Pages |
Abstract
⺠StCT2, a new antimicrobial peptide, was characterized from the venomous gland cDNA library of the Scorpiops tibetanus. ⺠The MICs of StCT2 for Staphylococcus aureus were 6.25-25 μg/ml, including antibiotic-resistant strains such as methicillin resistant S. aureus. ⺠StCT2 was found to show high in vivo antimicrobial activity by an S. aureus infection mouse model. ⺠StCT2 exerted its antimicrobial activity via a rapid bactericidal mechanism.
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Biochemistry
Authors
Luyang Cao, Zhongjie Li, Ruhong Zhang, Yingliang Wu, Wenxin Li, Zhijian Cao,