The structures of four bombesins and their cloned precursor-encoding cDNAs from acid-solvated skin secretion of the European yellow-bellied toad, Bombina variegata

► First demonstration of stability of both peptides and corresponding precursor-encoding mRNAs in long-term frozen (12 years) acid-solvated amphibian skin secretion. ► First demonstration of four different bombesins in the skin of a single amphibian species. ► First report of the novel analog, Asp2-, Phe4-SAP bombesin.