| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10835596 | Peptides | 2012 | 9 Pages |
Abstract
⺠Novel cationic amphipathic AMP GW-H1 has selective cytotoxicity against hepatocellular carcinoma (HCC) cell lines J5, Huh7, and Hep3B. ⺠GW-H1 induced caspase-dependent apoptosis of J5 HCC cell line. ⺠GW-H1 inhibited tumor growth of J5 xenografts in nude mice. ⺠GW-H1 possesses chemotherapeutic potential for the treatment of HCC.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Yi-Lin Sophia Chen, Jun-Hong Li, Chao-Yuan Yu, Ching-Ju Lin, Pai-Hsuan Chiu, Po-Wen Chen, Chai-Ching Lin, Wei-Jung Chen,