| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10835623 | Peptides | 2012 | 10 Pages |
Abstract
⺠W, WV and VW were shown to inhibit xanthine oxidase (XO) in a non-competitive fashion. ⺠W, WV and VW are 200 times less potent than Allopurinol a competitive drug of XO. ⺠Bovine lactoferrin (LF) hydrolyzed with gastrointestinal enzyme preparations generated W containing peptides could inhibit XO. ⺠Fractionation of a LF hydrolyzate with an activated carbon SPE cartridge allowed enrichment of W containing peptides. ⺠One SPE fraction enriched in W containing peptides was more potent than the hydrolyzate.
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Authors
Alice B. Nongonierma, Richard J. FitzGerald,