| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10835631 | Peptides | 2012 | 7 Pages |
Abstract
⺠Apelin enhances myocardial glucose uptake in vivo. ⺠Apelin triggers GLUT 4 translocation form cytosol to cell membrane. ⺠Apelin increases glucose uptake in cultured H9C2 cells. ⺠AMPK and IRS-1 participate in apelin's effect on glucose uptake in vivo and in vitro. ⺠Knockdown AMPK can inhibit apelin's effect on IRS-1 Ser-789 phosphorylation and glucose uptake.
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Authors
Shiming Xu, Pei Han, Mei Huang, Joseph C. Wu, Chingpin Chang, Philip S. Tsao, Patrick Yue,