| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10835642 | Peptides | 2012 | 6 Pages |
Abstract
⺠Two new peptides derived from mouse pro-NPFFA (crypteins) were synthesized. ⺠Effects of crypteins were compared with NPFF in the hot-plate and tail-immersion tests in mice. ⺠Both crypteins, similarly to NPFF, inhibited morphine-induced antinociception. ⺠Anti-opioid effects of crypteins were inhibited by NPFF receptors antagonist, RF9. ⺠Both crypteins derived from mouse NPFFA exert NPFF-like effects.
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Authors
Jolanta H. Kotlinska, Ewa Gibula-Bruzda, Piotr Suder, Magdalena Wasielak, Lauriane Bray, Hana Raoof, Anna Bodzon-Kulakowska, Jerzy Silberring,