Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10835648 | Peptides | 2012 | 11 Pages |
Abstract
⺠Limb ischemia-reperfusion (LIR) induced renal injury via oxidative stress in mice. ⺠Imbalance of ACE and ACE2 expression occurred in local kidney tissue in LIR mice. ⺠Loss of ACE2 worsened the imbalance of ACE and ACE2 and renal injury. ⺠These conditions were improved in ACE2 transgenic mice subjected to LIR.
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Authors
Xiu-hong Yang, Yin-huan Wang, Jian-jun Wang, Ying-chao Liu, Wei Deng, Chuan Qin, Jun-ling Gao, Lian-yuan Zhang,