Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10835656 | Peptides | 2012 | 8 Pages |
Abstract
⺠Well-known AMPs shows an antimycobacterial activity low and variable. ⺠The AMPs activity of the designed MIAP is 3-fold higher than the native peptide. ⺠AMPs partially inhibits the ATPase activity of mycobacterial plasma membrane vesicles. ⺠MIAP abolishes the F1F0-ATPase activity involved in H+ pumping across M. tuberculosis.
Keywords
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Biochemistry
Authors
Paola Santos, Aldemar Gordillo, Luis Osses, Luz-Mary Salazar, Carlos-Yesid Soto,