| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10835680 | Peptides | 2012 | 7 Pages |
Abstract
⺠Peptidomic analysis of skin secretions of the tetraploid frog Silurana epitropicalis has led to characterization of 10 antimicrobial peptides of the magainin, PGLa, CPF, and XPF families. ⺠Nonfunctionalization of antimicrobial peptides genes has occurred following polyploidization in the Siluran lineage. ⺠CPF-SE2 and CPF-SE3 show therapeutic potential for treatment of MRSA skin infections.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
J. Michael Conlon, Milena Mechkarska, Manju Prajeep, Agnes Sonnevend, Laurent Coquet, Jérôme Leprince, Thierry Jouenne, Hubert Vaudry, Jay D. King,