| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10835704 | Peptides | 2012 | 6 Pages |
Abstract
⺠We examined the recombinant hepcidin is effective in alleviating cholestasis-induced liver injury and mortality in mice with superimposed sepsis. ⺠Hepcidin pretreatment significantly reduced hepatic proinflammatory cytokine expression and liver injury in obstructive jaundice mice receiving LPS. ⺠Enhanced autophagy and reduced apoptosis may account for the protective effects of hepcidin.
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Authors
Ying-Hsien Huang, Ya-Ling Yang, Mao-Meng Tiao, Ho-Chang Kuo, Li-Tung Huang, Jiin-Haur Chuang,