| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10835808 | Peptides | 2012 | 7 Pages |
Abstract
⺠We set up a cell-based bioassay to screen for peptides with CCK1-receptor activity. ⺠A plate reader and a confocal microscope were compared to measure the Ca2+ increase. ⺠The plate reader assay allowed fast, high throughput screening. ⺠The microscope identified single-cell variations and factors reducing specificity. ⺠Both methods proved complementary to become a sensitive and selective assay.
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Authors
Dorien Staljanssens, Winnok H. De Vos, Peter Willems, John Van Camp, Guy Smagghe,