Article ID Journal Published Year Pages File Type
10835827 Peptides 2012 4 Pages PDF
Abstract
► The effect of orexin receptor type-1 antagonism on morphine tolerance was studied. ► Central injection of SB-334867 prior to morphine inhibited the development of analgesic tolerance. ► It is concluded that orexin might be involved in the development of tolerance to morphine.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Orexin receptor type-1 antagonist SB-334867 inhibits the development of morphine analgesic tolerance in rats
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