| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10835832 | Peptides | 2012 | 9 Pages |
Abstract
⺠Larazotide acetate (LA) inhibits gliadin-induced actin and ZO-1 redistribution. ⺠LA inhibits cytokine-induced permeability. ⺠LA inhibits gliadin translocation across Caco-2 cell monolayers. ⺠LA preserves tight junction structure and function in gluten-sensitive mice. ⺠LA is a novel compound with therapeutic value in celiac disease management.
Keywords
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Authors
Shobha Gopalakrishnan, Malarvizhi Durai, Kelly Kitchens, Amir P. Tamiz, Robert Somerville, Mark Ginski, Blake M. Paterson, Joseph A. Murray, Elena F. Verdu, Sefik S. Alkan, Niranjan B. Pandey,