Article ID Journal Published Year Pages File Type
10835850 Peptides 2011 7 Pages PDF
Abstract
► GLP-1 analog (GLP715a) containing an inter-disulfide bond and a Trp-cage extended its half-life. ► The analog (GLP715a) remained the biological activity of GLP-1. ► GLP715a showed better glucose tolerance and higher HbA1c reduction than GLP-1. ► GLP715a might be utilized as a long-lasting drug for type 2 diabetes.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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