Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10835850 | Peptides | 2011 | 7 Pages |
Abstract
⺠GLP-1 analog (GLP715a) containing an inter-disulfide bond and a Trp-cage extended its half-life. ⺠The analog (GLP715a) remained the biological activity of GLP-1. ⺠GLP715a showed better glucose tolerance and higher HbA1c reduction than GLP-1. ⺠GLP715a might be utilized as a long-lasting drug for type 2 diabetes.
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Authors
Ying Li, Weiren Xu, Lida Tang, Min Gong, Jianning Zhang,