Article ID Journal Published Year Pages File Type
10835869 Peptides 2011 11 Pages PDF
Abstract
► AM is a novel hypotensive peptide that exerts a variety of strongly protective effects against multiorgan damage. ► Many of the effects of AM are mediated via the RAMP2-based AM1 receptor. ► The evidence now suggests that the RAMP3-based AM2 receptor also has distinct functions in vivo. ► AM2 is an AM-related peptide whose biological actions are similar to those of AM. ► AM2 strongly interacts with the AM1 and AM2 receptors and may also bind to a unique receptor.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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