Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10835869 | Peptides | 2011 | 11 Pages |
Abstract
⺠AM is a novel hypotensive peptide that exerts a variety of strongly protective effects against multiorgan damage. ⺠Many of the effects of AM are mediated via the RAMP2-based AM1 receptor. ⺠The evidence now suggests that the RAMP3-based AM2 receptor also has distinct functions in vivo. ⺠AM2 is an AM-related peptide whose biological actions are similar to those of AM. ⺠AM2 strongly interacts with the AM1 and AM2 receptors and may also bind to a unique receptor.
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Authors
Kenji Kuwasako, Kazuo Kitamura, Sayaka Nagata, Tomomi Hikosaka, Yoshio Takei, Johji Kato,