Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10835870 | Peptides | 2011 | 15 Pages |
Abstract
⺠The renin-angiotensin system is now evolving as an endocrine, paracrine and intracrine system. ⺠The renin/ACE/Ang II/AT1 receptor axis is the most recognized cascade of the entire system. ⺠The prorenin/(Pro)renin receptor/MAP kinases ERK 1/2 axis is activated in diseased states. ⺠The ACE2/Ang (1-7) Mas receptor axis opposes the effects induced by Ang II via AT1 receptors.
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Authors
Jia L. Zhuo, Xiao C. Li,