| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10835876 | Peptides | 2012 | 9 Pages |
Abstract
⺠We tested toxicity of more than 60 peptides toward mammalian cells. ⺠Two normal cell lines (HUVEC and rat intestinal epithelial cells) were used. ⺠Three cancer cell lines (HeLa S3, CRC SW480 and CCRF-CEM T) were used. ⺠Most peptides are semi-selective for cancer cells, HeLa S3 cells are the most sensitive. ⺠The peptides are membranolytic.
Keywords
SW480AMPCEMTMREtetramethylrhodamineMICMEPHUVECDAPI4′,6-diamidino-2-phenylindole5,6-carboxyfluoresceinHuman colon adenocarcinomaTriton X-100Minimal inhibitory concentrationHuman umbilical vein endothelial cellsCancer cellsVenomToxicityMACConfocal microscopyHep G2HymenopteraPropidium iodideAntimicrobial peptideAntimicrobial peptidesHalIEC
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
JiÅina Slaninová, Veronika Mlsová, Hilda Kroupová, LukáÅ¡ Alán, Tereza Tůmová, Lenka Monincová, Lenka BoroviÄková, VladimÃr FuÄÃk, Václav ÄeÅovský,