Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10835907 | Peptides | 2011 | 8 Pages |
Abstract
⺠Processing and degradation of ghrelin and responsible enzymes in blood. ⺠Deacylation and truncation of ghrelin and responsible enzymes in blood are introduced. ⺠Acyl protein thioesterase 1 is an important ghrelin deacylation enzyme in serum. ⺠Significance of ghrelin-processing peptidases in plasma is proposed from MS analysis.
Keywords
Acyl protein thioesterase4-(2-aminoethyl)benzenesulfonyl fluorideGHSHDLMBOATAPT1EGR-1GHSRGSTAEBSFGHRHLysoPCPONAPTLC–MSGoatGrowth hormone secretagogueSerumliquid chromatography–mass spectrometryPlatelet activating factorLysophosphatidylcholineLysophospholipasehigh density lipoproteinlow density lipoproteinLDLMALDI-TOF MSPAFgrowth hormone releasing hormoneGrowth hormoneParaoxonaseearly growth response gene 1high performance liquid chromatographyHPLCGhrelinGhrelin O-acyltransferaseglutathione S-transferasegrowth hormone secretagogue receptor
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Authors
Motoyasu Satou, Yusuke Nakamura, Hiromi Ando, Hiroyuki Sugimoto,