Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1083592 | Journal of Clinical Epidemiology | 2006 | 11 Pages |
Abstract
The findings support the potential value of clinical databases to investigate treatment effectiveness. RCT simulation using the GPRD may be the most feasible way to assess observational study validity in comparison to RCTs. The extended GPRD study shows the feasibility of using a simulated study to supplement the results of an RCT of limited duration.
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Authors
Richard L. Tannen, Mark G. Weiner, Sue M. Marcus,