Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10835945 | Peptides | 2011 | 8 Pages |
Abstract
⺠The Atlantic cod mature cathelicidin antimicrobial peptide was characterized. ⺠It was active against a fungus and Gram-negative but not a Gram-positive bacterium. ⺠It demonstrated a rapidly lytic mode of action. ⺠It did not show cytotoxicity toward a fish cell line or mammalian membrane mimetics. ⺠It had no activity at physiological salinity and was cleaved by bacterial proteases.
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Authors
Daniela C. Broekman, Alexandra Zenz, Bjarnheidur K. Gudmundsdottir, Karl Lohner, Valerie H. Maier, Gudmundur H. Gudmundsson,