| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10835947 | Peptides | 2011 | 9 Pages |
Abstract
⺠VPAC1 is the exclusive, full-length VIP receptor expressed in early thymocyte progenitors (ETP). ⺠VPAC1 and VPAC2 undergo a transitory reversal in expression during thymocyte development. ⺠The transcription factor, Ikaros, may play a role in VPAC1 and VPAC2 reversal. ⺠VPAC2 knockout mouse and wild type controls show similar DN percentages. ⺠VIP signaling may contribute to thymocyte movement and/or protect thymocytes from cell death during early lymphopoiesis.
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Authors
Emilie E. Vomhof-DeKrey, Ashley R. Sandy, Jarrett J. Failing, Rebecca J. Hermann, Scott A. Hoselton, Jane M. Schuh, Abby J. Weldon, Kimberly J. Payne, Glenn P. Dorsam,