Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10835969 | Peptides | 2011 | 7 Pages |
Abstract
⺠SCAM of the first glucagon receptor extracellular loop (197-224). ⺠TM2 continues to position 202, TM3 from 215 ⺠Most side chains important for active glucagon conformation. ⺠S217 and D218 contact glucagon, V221 very close to the binding site. ⺠Receptor activation increases the accessibility of L198C mutant cysteine.
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Authors
David J. Roberts, Pascale Vertongen, Magali Waelbroeck,