Article ID Journal Published Year Pages File Type
10835969 Peptides 2011 7 Pages PDF
Abstract
► SCAM of the first glucagon receptor extracellular loop (197-224). ► TM2 continues to position 202, TM3 from 215 ► Most side chains important for active glucagon conformation. ► S217 and D218 contact glucagon, V221 very close to the binding site. ► Receptor activation increases the accessibility of L198C mutant cysteine.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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