Neuropeptide Y modulates functions of inflammatory cells in the rat: Distinct role for Y1, Y2 and Y5 receptors

Article ID	Journal	Published Year	Pages	File Type
10835973	Peptides	2011	8 Pages	PDF

Abstract

âº Inflammatory cells express Y1, Y2 and Y5 receptor subtypes. âº NPY in vivo suppresses inflammatory cells functions via Y2/Y5 receptors. âº NPY in vitro stimulates leukocytes functions via Y1 receptor. âº Anti-inflammatory effect of NPY depends on Y receptors interplay and DP4 activity.

Keywords

NBT DP4 NPY ODS LPS PBS MPO inflammation Nitro blue tetrazolium chloride optical densities dipeptidyl peptidase 4 Phosphate buffered saline lipopolysaccharide MEM Rat Monocytes myeloperoxidase Granulocytes Neuropeptide Y

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

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Neuropeptide Y modulates functions of inflammatory cells in the rat: Distinct role for Y1, Y2 and Y5 receptors

Authors

Katarina MitiÄ, Stanislava StanojeviÄ, NataÅ¡a KuÅ¡trimoviÄ, Vesna VujiÄ, Mirjana DimitrijeviÄ,