Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10835979 | Peptides | 2011 | 11 Pages |
Abstract
⺠Prazosin, an α1-adrenoceptor blocker, is an effect treatment for post-traumatic stress disorder.
- Prazosin modulates release of TRH and TRH-like peptides in rat brain and peripheral tissues. ⺠TRH and TRH-like peptides have neuroprotective, antidepressant, and anxiolytic effects. ⺠These peptides may mediate some of the therapeutic effects of prozosin.
- Prazosin modulates release of TRH and TRH-like peptides in rat brain and peripheral tissues. ⺠TRH and TRH-like peptides have neuroprotective, antidepressant, and anxiolytic effects. ⺠These peptides may mediate some of the therapeutic effects of prozosin.
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Authors
Albert Sattin, Albert Eugene Pekary, James Blood,