Article ID Journal Published Year Pages File Type
10835979 Peptides 2011 11 Pages PDF
Abstract
► Prazosin, an α1-adrenoceptor blocker, is an effect treatment for post-traumatic stress disorder.
- Prazosin modulates release of TRH and TRH-like peptides in rat brain and peripheral tissues. ► TRH and TRH-like peptides have neuroprotective, antidepressant, and anxiolytic effects. ► These peptides may mediate some of the therapeutic effects of prozosin.
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