Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10835980 | Peptides | 2011 | 8 Pages |
Abstract
- BRS-3 agonists stimulate the proliferation of lung cancer cells. BRS-3 ant. increased the cytotoxicity of gefitinib.
- BRS-3 agonists increased the tyrosine phosphorylation of EGF receptor in lung cancer cells.
- The EGF receptor tyrosine phosphorylation causes by addition of BRS-3 agonists to lung cancer cells occurs in a Src-, MMP- and oxygen-dependent manner.
Keywords
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Biochemistry
Authors
Terry W. Moody, Veronica Sancho, Alessia di Florio, Bernardo Nuche-Berenguer, Samuel Mantey, Robert T. Jensen,