Article ID Journal Published Year Pages File Type
10837822 Pharmacology Biochemistry and Behavior 2012 6 Pages PDF
Abstract
► Nitric oxide is implicated in the mechanism of action of antidepressant drugs. ► Sildenafil is often used concomitantly with antidepressant drugs. ► Effect of sildenafil on the activity of bupropion and venlafaxine was investigated. ► Sildenafil potentiated the anti-immobility action of the studied drugs. ► The interactions may have pharmacodynamic and/or pharmacokinetic basis.
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