Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10837822 | Pharmacology Biochemistry and Behavior | 2012 | 6 Pages |
Abstract
⺠Nitric oxide is implicated in the mechanism of action of antidepressant drugs. ⺠Sildenafil is often used concomitantly with antidepressant drugs. ⺠Effect of sildenafil on the activity of bupropion and venlafaxine was investigated. ⺠Sildenafil potentiated the anti-immobility action of the studied drugs. ⺠The interactions may have pharmacodynamic and/or pharmacokinetic basis.
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Authors
Katarzyna SocaÅa, Dorota Nieoczym, Elżbieta Wyska, Ewa Poleszak, Piotr Wlaź,