Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10837834 | Pharmacology Biochemistry and Behavior | 2012 | 8 Pages |
Abstract
⺠Neurosteroids, such as allopregnanolone (ALLO), are modulators of the GABAA receptor. ⺠ALLO plays an important role in the pathophysiology of depression and anxiety. ⺠ALLO alters the hippocampal mRNA expression of γ2 and δ GABAA receptor subunits. ⺠There are asymmetrical changes in GABAA receptor mRNA expression after ALLO treatment.
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Authors
MaurÃcio S. Nin, Marcelo K. Ferri, Natividade S. Couto-Pereira, Marilise F. Souza, Lucas A. Azeredo, Grasiela Agnes, Rosane Gomez, Helena M.T. Barros,