| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10837839 | Pharmacology Biochemistry and Behavior | 2012 | 8 Pages |
Abstract
⺠Effects of tianeptine in animal submitted to stress protocol. ⺠Tianeptine did not alter IL-1, IL-6 and TNF-α in all structures. ⺠Tianeptine decreased the MDA equivalents in control groups. ⺠Tianeptine increased the SOD and CAT activities.
Keywords
HPCTBARSMDDRNSNACCATPFCIL-1IL-6LPSMDAROSAmygdalaMajor depressive disorderChronic stresschronic mild stressDepressionAMYinterleukin-6interleukin-1Oxidative stressTianeptineSODSuperoxide dismutaseCytokinestumor necrosis factorTNF-αprefrontal cortexlipopolysaccharidemalondialdehydethiobarbituric acid reactive substancesNucleus accumbensHippocampusCatalasereactive nitrogen speciesReactive oxygen species
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Authors
Franciela P. Della, Helena M. Abelaira, Gislaine Z. Réus, Altamir R. Antunes, Maria Augusta B. dos Santos, Giovanni Zappelinni, Amanda V. Steckert, Francieli Vuolo, LetÃcia S. Galant, Felipe Dal-Pizzol, Flávio Kapczinski, João Quevedo,