Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10837842 | Pharmacology Biochemistry and Behavior | 2012 | 7 Pages |
Abstract
⺠mGluR5 agonist CHPG attenuated toluene-induced behavioral changes and hypothermia. ⺠Blockade of mGluR5 potentiated behavioral changes and hypothermia by toluene. ⺠Inhibition of PKC reversed the attenuating effect of CHPG on toluene's responses. ⺠mGluR5 may modulate certain responses of toluene in a PKC-dependent manner.
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Authors
Ming-Huan Chan, Chia-Chi Lee, Bih-Fen Lin, Chia-Yen Wu, Hwei-Hsien Chen,