Article ID Journal Published Year Pages File Type
10837856 Pharmacology Biochemistry and Behavior 2012 5 Pages PDF
Abstract
► Acute treatment with morphine increased the extracellular levels of dopamine into the VTA. ► The lesion of mPFC before morphine administration attenuated the effects of morphine on the level of dopamine into the VTA. ► The mPFC exert a modulator effect on mesocorticolimbic rewarding system.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Lesion of medial prefrontal cortex reduces morphine-induced extracellular dopamine level in the ventral tegmental area: A microdialysis study in rats
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