| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10837857 | Pharmacology Biochemistry and Behavior | 2012 | 6 Pages |
Abstract
⺠Mirtazapine reversed the PPI impairment caused by amphetamine. ⺠Mirtazapine was not effective in reversing the PPI impairment caused by dizocilpine. ⺠H1, α2 adrenergic, and possibly 5-HT antagonist effects of mirtazapine contribute to its efficacy in reversing PPI deficits caused by amphetamine. ⺠The muscarinic antagonism of mirtazapine may limit mirtazapine's efficacy.
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Authors
José A. Larrauri, Edward D. Levin,