| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10837863 | Pharmacology Biochemistry and Behavior | 2012 | 9 Pages |
Abstract
⺠Novelty-seeking can predict the sensitivity to the rewarding properties of cocaine. ⺠CPP was induced with a sub-threshold dose of cocaine (1 mg/kg, i.p.). ⺠Three factors were considered: age, sex and novelty-seeking trait. ⺠High-environment-NS young adult mice developed cocaine-induced CPP. ⺠Time spent exploring novel environment can identify animals more vulnerable to drugs.
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Authors
Antonio Vidal-Infer, M. Carmen Arenas, Manuel Daza-Losada, Mª. Asunción Aguilar, José Miñarro, Marta RodrÃguez-Arias,