Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10837876 | Pharmacology Biochemistry and Behavior | 2012 | 6 Pages |
Abstract
⺠AMPA receptors are involved in the behavioral effects of mGluR7 agonist AMN082 administration. ⺠AMN082-induced decreased of immobility in the tail suspension test is attenuated by NBQX. ⺠AMN082 alters the phosphorylation of GluR1, NR1, NR2b subunits in the hippocampus. ⺠mGluR7 activation could be an alternative to NMDARs blockers in the treatment of mood disorders.
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Authors
Stefania Risso Bradley, Jason M. Uslaner, Rose B. Flick, Ariel Lee, Kristina M. Groover, Peter H. Hutson,