Article ID Journal Published Year Pages File Type
10837887 Pharmacology Biochemistry and Behavior 2012 8 Pages PDF
Abstract
► Prepulse inhibition is disrupted by muscarinic cholinergic blocker in mice. ► The effect is centrally mediated and independent of its effect on startle reactivity. ► Clozapine antagonizes the PPI-disruptive effect of scopolamine. ► A drug-induced PPI deficit model uniquely responsive to typical/atypical neuroleptics.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, ,