Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10837887 | Pharmacology Biochemistry and Behavior | 2012 | 8 Pages |
Abstract
⺠Prepulse inhibition is disrupted by muscarinic cholinergic blocker in mice. ⺠The effect is centrally mediated and independent of its effect on startle reactivity. ⺠Clozapine antagonizes the PPI-disruptive effect of scopolamine. ⺠A drug-induced PPI deficit model uniquely responsive to typical/atypical neuroleptics.
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Authors
Philipp Singer, Benjamin K. Yee,