| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10837903 | Pharmacology Biochemistry and Behavior | 2012 | 6 Pages |
Abstract
⺠Imidazoline I2 receptor agonists decreased food-maintained responding. ⺠I2 receptor agonists and morphine produced additive or infra-additive interactions in decreasing food-maintained responding. ⺠The nature of the interaction depended on the proportions of morphine and I2 receptor agonists in the mixture. ⺠That I2 receptor agonists enhance the antinociceptive but not response-decreasing effects of morphine supports combining I2 agonists and morphine for pain treatment.
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Authors
Xiao-Fei An, Yanan Zhang, Jerrold C. Winter, Jun-Xu Li,