Article ID Journal Published Year Pages File Type
10837912 Pharmacology Biochemistry and Behavior 2012 9 Pages PDF
Abstract
► We examined the effects of variable stress on nicotine behavioral sensitization. ► Molecular assays to evaluate CREB and ERK activity. ► Effects of variable stress on nicotine-seeking behavior. ► Stress caused a sensitized motor response and decrease CREB in the nucleus accumbens. ► Stress exposure caused an increase in the break point and nicotine intake.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Stress induces behavioral sensitization, increases nicotine-seeking behavior and leads to a decrease of CREB in the nucleus accumbens
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